Saddest Cities in U.S. Are St. Petersburg, Detroit and Memphis: Report

Saddest Cities in U.S. Are St. Petersburg, Detroit and Memphis: Report - St. Petersburg, Fl., is apparently the saddest city in America, with Detroit, Mi. not far behind, according to a study by Men's Health magazine, which used data such as unemployment and suicid rates, antidepressant usage and the number of people who actually admitted to depression.